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KRT20 Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession P35900
Additional Information
Gene ID 54474
Other Names Keratin, type I cytoskeletal 20, Cytokeratin-20, CK-20, Keratin-20, K20, Protein IT, KRT20
Target/Specificity The synthetic peptide sequence is selected from aa 387-401 of Human KRT20
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT20
Function Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
Cellular Location Cytoplasm
Tissue Location Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.
Research Areas
Citations (0)

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Background

Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).

References

Moll R., et al. Differentiation 53:75-93(1993).
Ota T., et al. Nat. Genet. 36:40-45(2004).
Zhou Q., et al. J. Biol. Chem. 281:16453-16461(2006).
Calnek D., et al. Differentiation 53:95-104(1993).
Moll R., et al. J. Cell Biol. 111:567-580(1990).

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$ 80.00
Cat# BP20533b
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