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POLR2J3 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H1A7 |
|---|---|
| Other Accession | Q9GZM3 |
| Gene ID | 548644 |
|---|---|
| Other Names | DNA-directed RNA polymerase II subunit RPB11-b2, RNA polymerase II subunit B11-b2, RPB11b2, DNA-directed RNA polymerase II subunit J3, POLR2J3 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 14-25 of HUMAN POLR2J3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | POLR2J3 |
|---|---|
| Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity).
References
Grandemange S.,et al.BMC Mol. Biol. 2:14-14(2001).
Hillier L.W.,et al.Nature 424:157-164(2003).
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