EIF4G2 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P78344 |
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Other Accession | P79398, Q62448, Q95L46 |
Gene ID | 1982 |
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Other Names | Eukaryotic translation initiation factor 4 gamma 2, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, Death-associated protein 5, DAP-5, p97, EIF4G2 (HGNC:3297) |
Target/Specificity | The synthetic peptide sequence is selected from aa 30-44 of HUMAN EIF4G2 (HGNC:3297) |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | EIF4G2 (HGNC:3297) |
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Function | Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases. |
Tissue Location | Ubiquitously expressed in all adult tissues examined, with high levels in skeletal muscle and heart. Also expressed in fetal brain, lung, liver and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.
References
Imataka H.,et al.EMBO J. 16:817-825(1997).
Yamanaka S.,et al.Genes Dev. 11:321-333(1997).
Levy-Strumpf N.,et al.Mol. Cell. Biol. 17:1615-1625(1997).
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).
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