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GSTT1 Blocking Peptide (N-term)

Synthetic peptide

     
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Product Information
Primary Accession P30711
Additional Information
Gene ID 2952
Other Names Glutathione S-transferase theta-1, GST class-theta-1, Glutathione transferase T1-1, GSTT1
Target/Specificity The synthetic peptide sequence is selected from aa 46-59 of HUMAN GSTT1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GSTT1
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2- epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4- nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide.
Cellular Location Cytoplasm.
Tissue Location Found in erythrocyte. Expressed at low levels in liver. In lung, expressed at low levels in Clara cells and ciliated cells at the alveolar/bronchiolar junction. Absent from epithelial cells of larger bronchioles
Research Areas
Citations (0)

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Background

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2- epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4- nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide.

References

Pemble S.,et al.Biochem. J. 300:271-276(1994).
Jemth P.,et al.Arch. Biochem. Biophys. 348:247-254(1997).
Sprenger R.,et al.Pharmacogenetics 10:557-565(2000).
Iida A.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.

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$ 80.00
Cat# BP20614a
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