|Other Names||Recoverin, Cancer-associated retinopathy protein, Protein CAR, RCVRN, RCV1|
|Target/Specificity||The synthetic peptide sequence is selected from aa 137-151 of HUMAN RCVRN|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.|
|Tissue Location||Retina and pineal gland.|
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Provided below are standard protocols that you may find useful for product applications.
Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.
Murakami A.,et al.Biochem. Biophys. Res. Commun. 187:234-244(1992).
Wiechmann A.F.,et al.Exp. Eye Res. 56:463-470(1993).
Thirkill C.E.,et al.Invest. Ophthalmol. Vis. Sci. 33:2768-2772(1992).
Matsubara S.,et al.Br. J. Cancer 74:1419-1422(1996).
Polans A.S.,et al.J. Cell Biol. 112:981-989(1991).
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