TIMM50 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q3ZCQ8 |
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Gene ID | 92609 |
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Other Names | Mitochondrial import inner membrane translocase subunit TIM50, TIMM50, TIM50 |
Target/Specificity | The synthetic peptide sequence is selected from aa 25-36 of HUMAN TIMM50 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TIMM50 |
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Synonyms | TIM50 |
Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. |
Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein |
Tissue Location | Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level) |
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Provided below are standard protocols that you may find useful for product applications.
Background
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.
References
Guo Y.,et al.J. Biol. Chem. 279:24813-24825(2004).
Zheng H.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Grimwood J.,et al.Nature 428:529-535(2004).
Zhang C.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (JUN-2005) to UniProtKB.
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