IMMT Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q16891 |
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Gene ID | 10989 |
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Other Names | MICOS complex subunit MIC60, Cell proliferation-inducing gene 4/52 protein, Mitochondrial inner membrane protein, Mitofilin, p87/89, IMMT, HMP, MIC60, MINOS2 |
Target/Specificity | The synthetic peptide sequence is selected from aa 170-183 of HUMAN IMMT |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | IMMT |
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Synonyms | HMP, MIC60, MINOS2 |
Function | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180). |
Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion |
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Provided below are standard protocols that you may find useful for product applications.
References
Icho T.,et al.Gene 144:301-306(1994).
Gieffers C.,et al.Exp. Cell Res. 232:395-399(1997).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kim J.W.,et al.Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
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