|Other Names||Platelet glycoprotein Ib alpha chain, GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha, CD42b, Glycocalicin, GP1BA|
|Target/Specificity||The synthetic peptide sequence is selected from aa 344-358 of HUMAN GP1BA|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.
Lopez J.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:5615-5619(1987).
Wenger R.H.,et al.Biochem. Biophys. Res. Commun. 156:389-395(1988).
Matsubara Y.,et al.Thromb. Haemost. 87:867-872(2002).
Matsubara Y.,et al.J. Thromb. Haemost. 1:2198-2205(2003).
Titani K.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:5610-5614(1987).
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