|Other Names||Glutaredoxin-related protein 5, mitochondrial, Monothiol glutaredoxin-5, GLRX5, C14orf87|
|Target/Specificity||The synthetic peptide sequence is selected from aa 93-107 of HUMAN GLRX5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (PubMed:20364084). Involved in protein lipoylation, acting in the pathway that provides an iron-sulfur cluster to lipoate synthase (PubMed:24334290). Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 (PubMed:20364084). May protect cells against apoptosis due to reactive oxygen species and oxidative stress (By similarity).|
|Cellular Location||Mitochondrion matrix|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.
Wingert R.A.,et al.Nature 436:1035-1039(2005).
Wingert R.A.,et al.Nature 437:920-920(2005).
Kurosawa N.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Li W.B.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
If you have any additional inquiries please email technical services at email@example.com.