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Mouse T Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession P20293
Additional Information
Gene ID 20997
Other Names Brachyury protein, Protein T, T
Target/Specificity The synthetic peptide sequence is selected from aa 408-422 of HUMAN T
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tbxt {ECO:0000250|UniProtKB:O15178}
Function Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation (PubMed:7588606). Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site (PubMed:8344258, PubMed:7588606).
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.

References

Herrmann B.G.,et al.Nature 343:617-622(1990).
Kispert A.,et al.EMBO J. 12:3211-3220(1993).
Kispert A.,et al.EMBO J. 14:4763-4772(1995).

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$ 277.78
Cat# BP20762c
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