|Other Names||Synaptonemal complex protein 3, SCP-3, SYCP3, SCP3|
|Target/Specificity||The synthetic peptide sequence is selected from aa 13-26 of HUMAN SYCP3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).|
|Cellular Location||Nucleus. Chromosome. Note=In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed.|
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Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).
Martinez-Garay I.,et al.Genomics 80:259-267(2002).
Adamah D.J.B.,et al.Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
Miyamoto T.,et al.Lancet 362:1714-1719(2003).
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