Mouse Gata6 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q61169 |
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Other Accession | P46153, P43693 |
Gene ID | 14465 |
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Other Names | Transcription factor GATA-6, GATA-binding factor 6, Gata6 |
Target/Specificity | The synthetic peptide sequence is selected from aa 485-498 of HUMAN Gata6 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | Gata6 |
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Function | Transcriptional activator that regulates SEMA3C and PLXNA2 (PubMed:19666519). May regulate genes that protect epithelial cells from bacterial infection (By similarity). Involved in gene regulation specifically in the gastric epithelium (By similarity). Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (PubMed:15329343). Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (PubMed:15329343). |
Cellular Location | Nucleus. |
Tissue Location | Expressed in myocardium, vascular smooth muscle, gut epithelium, and osteoclasts |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional activator that regulates SEMA3C and PLXNA2. Involved in gene regulation specifically in the gastric epithelium (By similarity).
References
Morrisey E.E.,et al.Dev. Biol. 177:309-322(1996).
Katsuoka F.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Narita N.,et al.Genomics 36:345-348(1996).
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