Mouse Hmga2 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P52927 |
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Other Accession | P52926 |
Gene ID | 15364 |
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Other Names | High mobility group protein HMGI-C, High mobility group AT-hook protein 2, Hmga2, Hmgic |
Target/Specificity | The synthetic peptide sequence is selected from aa 72-85 of HUMAN Hmga2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | Hmga2 |
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Synonyms | Hmgic |
Function | Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (PubMed:27446912). Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner (By similarity). |
Cellular Location | Nucleus. |
Tissue Location | Expressed in mitotic spermatogonia, meiotic spermatocytes, and postmeiotic round spermatids (at protein level) (PubMed:14668482). Expressed in embryonic myogenic progenitor cells (PubMed:27446912). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes.
References
Manfioletti G.,et al.Nucleic Acids Res. 19:6793-6797(1991).
Manfioletti G.,et al.Gene 167:249-253(1995).
Zhou X.,et al.Nucleic Acids Res. 24:4071-4077(1996).
Carninci P.,et al.Science 309:1559-1563(2005).
Di Agostino S.,et al.Mol. Biol. Cell 15:1224-1232(2004).
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