|Other Names||Transcription factor GATA-6, GATA-binding factor 6, GATA6|
|Target/Specificity||The synthetic peptide sequence is selected from aa 551-565 of HUMAN GATA6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional activator that regulates SEMA3C and PLXNA2 (PubMed:19666519). Involved in gene regulation specifically in the gastric epithelium (PubMed:9315713). May regulate genes that protect epithelial cells from bacterial infection (PubMed:16968778). Involved in bone morphogenetic protein (BMP)- mediated cardiac-specific gene expression (By similarity). Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity).|
|Tissue Location||Expressed in heart, gut and gut-derived tissues|
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation.
Suzuki E.,et al.Genomics 38:283-290(1996).
Huggon I.C.,et al.Biochim. Biophys. Acta 1353:98-102(1997).
Yoshida T.,et al.FEBS Lett. 414:333-337(1997).
Nusbaum C.,et al.Nature 437:551-555(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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