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CXCL16 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q9H2A7
Additional Information
Gene ID 58191
Other Names C-X-C motif chemokine 16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, SR-PSOX, Small-inducible cytokine B16, Transmembrane chemokine CXCL16, CXCL16, SCYB16, SRPSOX
Target/Specificity The synthetic peptide sequence is selected from aa 150-163 of HUMAN CXCL16
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CXCL16
Synonyms SCYB16, SRPSOX
Function Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
Cellular Location Cell membrane; Single-pass type I membrane protein. Secreted. Note=Also exists as a soluble form
Tissue Location Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus Weak expression in heart and liver and no expression in brain and bone marrow
Research Areas
Citations (0)

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Background

Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.

References

Matloubian M.,et al.Nat. Immunol. 1:298-304(2000).
Wilbanks A.,et al.J. Immunol. 166:5145-5154(2001).
Shimaoka T.,et al.J. Biol. Chem. 275:40663-40666(2000).
Livingston R.J.,et al.Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).

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$ 80.00
Cat# BP20991a
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