CXCL16 Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H2A7 |
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Gene ID | 58191 |
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Other Names | C-X-C motif chemokine 16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, SR-PSOX, Small-inducible cytokine B16, Transmembrane chemokine CXCL16, CXCL16, SCYB16, SRPSOX |
Target/Specificity | The synthetic peptide sequence is selected from aa 150-163 of HUMAN CXCL16 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CXCL16 |
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Synonyms | SCYB16, SRPSOX |
Function | Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Secreted. Note=Also exists as a soluble form |
Tissue Location | Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow |
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Provided below are standard protocols that you may find useful for product applications.
Background
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
References
Matloubian M.,et al.Nat. Immunol. 1:298-304(2000).
Wilbanks A.,et al.J. Immunol. 166:5145-5154(2001).
Shimaoka T.,et al.J. Biol. Chem. 275:40663-40666(2000).
Livingston R.J.,et al.Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
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