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LIFR Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession P42702
Additional Information
Gene ID 3977
Other Names Leukemia inhibitory factor receptor, LIF receptor, LIF-R, CD118, LIFR
Target/Specificity The synthetic peptide sequence is selected from aa 1021-1035 of HUMAN LIFR
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LIFR
Function Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.

References

Gearing D.P.,et al.EMBO J. 10:2839-2848(1991).
Wang Z.,et al.Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.
Voz M.L.,et al.Oncogene 16:1409-1416(1998).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Skiniotis G.,et al.Mol. Cell 31:737-748(2008).

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$ 80.00
$ 99.00
Cat# BP21029c
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