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LIFR Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P42702 |
|---|
| Gene ID | 3977 |
|---|---|
| Other Names | Leukemia inhibitory factor receptor, LIF receptor, LIF-R, CD118, LIFR |
| Target/Specificity | The synthetic peptide sequence is selected from aa 1021-1035 of HUMAN LIFR |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LIFR |
|---|---|
| Function | Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells. |
| Cellular Location | [Isoform 1]: Cell membrane; Single-pass type I membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
References
Gearing D.P.,et al.EMBO J. 10:2839-2848(1991).
Wang Z.,et al.Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.
Voz M.L.,et al.Oncogene 16:1409-1416(1998).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Skiniotis G.,et al.Mol. Cell 31:737-748(2008).
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