|Other Names||Zinc finger protein DZIP1, DAZ-interacting protein 1/2, DZIP1, DZIP, DZIP2, KIAA0996|
|Target/Specificity||The synthetic peptide sequence is selected from aa 747-761 of HUMAN DZIP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||DZIP, DZIP2, KIAA0996|
|Function||May participate in spermatogenesis via its interaction with DAZ (PubMed:15081113). Has a role in primary cilium formation (PubMed:19852954).|
|Cellular Location||Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=In testis, it is predominantly nuclear, with some cytoplasmic localization in spermatogonia Colocalizes with DAZ and DAZL in primordial germ cells|
|Tissue Location||Predominantly expressed in testis. Also expressed in fetal brain, adult oocytes and ovary. Expressed in undifferentiated ES cells. In testis, it is probably specifically expressed in germ cells. Expressed in mature germ cells and secondary spermatocytes, while it is weakly or not expressed in primary spermatocytes.|
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May participate in spermatogenesis via its interaction with DAZ.
Moore F.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:538-543(2003).
Nagase T.,et al.DNA Res. 6:63-70(1999).
Dunham A.,et al.Nature 428:522-528(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Moore F.L.,et al.Genomics 83:834-843(2004).
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