|Other Names||Microsomal triglyceride transfer protein large subunit, MTTP, MTP|
|Target/Specificity||The synthetic peptide sequence is selected from aa 878-891 of HUMAN MTTP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:23475612, PubMed:8939939, PubMed:26224785, PubMed:25108285, PubMed:22236406). Required for the secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:23475612, PubMed:8939939, PubMed:26224785).|
|Cellular Location||Endoplasmic reticulum. Note=Colocalizes with P4HB/PDI in the endoplasmic reticulum (PubMed:23475612, PubMed:26224785)|
|Tissue Location||Liver and small intestine. Also found in ovary, testis and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B.
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Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hagan D.L.,et al.J. Biol. Chem. 269:28737-28744(1994).
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