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NR4A2 Blocking Peptide (Center)

Synthetic peptide

     
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  • CITATIONS
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Product Information
Primary Accession P43354
Other Accession Q07917, Q06219, Q08E53
Additional Information
Gene ID 4929
Other Names Nuclear receptor subfamily 4 group A member 2, Immediate-early response protein NOT, Orphan nuclear receptor NURR1, Transcriptionally-inducible nuclear receptor, NR4A2, NOT, NURR1, TINUR
Target/Specificity The synthetic peptide sequence is selected from aa 380-392 of HUMAN NR4A2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NR4A2
Synonyms NOT, NURR1, TINUR
Function Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity).
Cellular Location Cytoplasm. Nucleus. Note=Mostly nuclear; oxidative stress promotes cytoplasmic localization
Tissue Location Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue
Research Areas
Citations (0)

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Background

Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity).

References

Mages H.W.,et al.Mol. Endocrinol. 8:1583-1591(1994).
Ichinose H.,et al.Gene 230:233-239(1999).
Torii T.,et al.Gene 230:225-232(1999).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 80.00
$ 99.00
Cat# BP21092a
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