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Mouse Lhx1 Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession P63006
Other Accession P63007, P48742
Additional Information
Gene ID 16869
Other Names LIM/homeobox protein Lhx1, LIM homeobox protein 1, Homeobox protein Lim-1, Lhx1, Lim-1, Lim1
Target/Specificity The synthetic peptide sequence is selected from aa 332-345 of HUMAN Lhx1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Lhx1
Synonyms Lim-1, Lim1
Function Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:8793615}
Tissue Location In mid to late stage embryos, expressed in a restricted region of mesoderm in the primitive streak. At 7.5 days, expressed in a horseshoe shape at the periphery of the node, as well as along both sides of the adjacent notochord. Also present in presumptive lateral and intermediate mesoderm. Later, expression become progressively restricted to intermediate mesoderm, and the developing excretory system including the pronephric region, mesonephros, nephric duct and metanephros. In the metanephros, strongly expressed in renal vesicles and S-shaped and coma-shaped bodies, as well as in the ureteric bud and its derivatives. Also expressed in the dorsal root ganglia. By stage 10.5, also expressed in regions of the central nervous system in the telencephalon through to the spinal cord. In adults, expressed in the cerebellum/medulla and kidney, and at very low levels in the cerebrum.
Research Areas
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Background

Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.

References

Fujii T.,et al.Dev. Dyn. 199:73-83(1994).
Barnes J.D.,et al.Dev. Biol. 161:168-178(1994).
Li Y.,et al.Mamm. Genome 10:444-446(1999).
Karavanov A.A.,et al.Int. J. Dev. Biol. 40:453-461(1996).
Agulnick A.D.,et al.Nature 384:270-272(1996).

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$ 80.00
$ 99.00
Cat# BP21094a
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