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UBE4A Antibody (C-term) Blocking PeptideSynthetic peptide
| Country | United States
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| Catalog # | Size | Availability | Price | |
| BP2110b | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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UBE4A Antibody (C-term) Blocking Peptide - Product info | |
| Primary Accession | Q14139 |
| Other Accession | NP_004779 |
| Clone Names | 3061109 |
| Calculated MW | 122561 Da |
UBE4A Antibody (C-term) Blocking Peptide - Additional info | |
| Gene ID 9354 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP2110b was selected from the C-term region of human UBE4A . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
UBE4A Antibody (C-term) Blocking Peptide - Protein Information | |
| Name UBE4A | |
| Synonyms KIAA0126 | |
| Function Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3 (By similarity) | |
UBE4A Antibody (C-term) Blocking Peptide - Related products
AP2110b: UBE4A Antibody (C-term)
RI15590: UBE4A predesign siRNA
UBE4A Antibody (C-term) Blocking Peptide - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins.1 Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4.2 In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.
REFERENCES
Nagase, T., et al., DNA Res. 2(4):167-174 (1995).
