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UBE4A Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q14139
Other Accession NP_004779
Clone Names 3061109
Peptide ID 3061109
Additional Information
Gene ID 9354
Other Names Ubiquitin conjugation factor E4 A, 632-, UBE4A (HGNC:12499)
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2110b was selected from the C-term region of human UBE4A . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBE4A (HGNC:12499)
Function Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:E9Q735}.
Research Areas
Citations (0)

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Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins.1 Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4.2 In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.


Nagase, T., et al., DNA Res. 2(4):167-174 (1995).

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$ 80.00
Cat# BP2110b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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