|Other Names||Somatostatin receptor type 1, SS-1-R, SS1-R, SS1R, SRIF-2, SSTR1|
|Target/Specificity||The synthetic peptide sequence is selected from aa 367-383 of HUMAN SSTR1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
Yamada Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:251-255(1992).
Kopatz S.A.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Schwaerzler A.,et al.J. Biol. Chem. 275:9557-9562(2000).
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