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UBE2L6 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O14933
Other Accession NP_937826
Clone Names 3061612
Peptide ID 3061612
Additional Information
Gene ID 9246
Other Names Ubiquitin/ISG15-conjugating enzyme E2 L6, Retinoic acid-induced gene B protein, RIG-B, UbcH8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, UBE2L6, UBCH8
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2118a was selected from the N-term region of human UBE2L6 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBE2L6
Synonyms UBCH8
Function Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
Tissue Location Present in natural killer cells (at protein level).
Research Areas
Citations (0)

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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.


Kumar, S., et al., J. Biol. Chem. 272(21):13548-13554 (1997).Ardley, H.C., et al., Cytogenet. Cell Genet. 89 (1-2), 137-140 (2000).

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$ 80.00
Cat# BP2118a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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