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ATP2B3 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q16720 |
|---|
| Gene ID | 492 |
|---|---|
| Target/Specificity | The synthetic peptide sequence is selected from aa 1161-1174 of HUMAN ATP2B3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ATP2B3 {ECO:0000303|PubMed:8187550, ECO:0000312|HGNC:HGNC:816} |
|---|---|
| Function | ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals (PubMed:25953895, PubMed:27035656, PubMed:22912398, PubMed:18029012). Uses ATP as an energy source to transport cytosolic Ca(2+) ions across the plasma membrane to the extracellular compartment (PubMed:25953895, PubMed:27035656). May counter-transport protons, but the mechanism and the stoichiometry of this Ca(2+)/H(+) exchange remains to be established (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Presynaptic cell membrane {ECO:0000250|UniProtKB:Q64568}; Multi-pass membrane protein. Note=Localized at parallel fiber terminals {ECO:0000250|UniProtKB:Q64568} |
| Tissue Location | Highly expressed in the cerebellum (PubMed:8187550). Expressed in adrenal glands (PubMed:27035656) |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
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$ 277.78
Cat# BP21234b
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