BZRAP1 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O95153 |
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Gene ID | 9256 |
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Other Names | Peripheral-type benzodiazepine receptor-associated protein 1, PRAX-1, Peripheral benzodiazepine receptor-interacting protein, PBR-IP, RIMS-binding protein 1, RIM-BP1, BZRAP1, KIAA0612, RBP1, RIMBP1 |
Target/Specificity | The synthetic peptide sequence is selected from aa 1551-1565 of HUMAN BZRAP1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TSPOAP1 (HGNC:16831) |
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Function | Required for synaptic transmission regulation (PubMed:33539324). It probably controls the recruitement of voltage- gated calcium channels to the presynaptic membrane, and modulates neurotransmitter release. |
Cellular Location | Cytoplasm. Mitochondrion. Note=Preferentially expressed in the mitochondria in the presence of TSPO |
Tissue Location | Predominantly expressed in brain, pituitary gland and thymus in adults. In adult brain, highest expression found in temporal lobe and the putamen, followed by amygdala, caudate nucleus, cerebral cortex, occipital and frontal lobe. A high expression level is also observed in fetal tissues like brain, heart, kidney and thymus |
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Provided below are standard protocols that you may find useful for product applications.
References
Galiegue S.,et al.J. Biol. Chem. 274:2938-2952(1999).
Ishikawa K.,et al.DNA Res. 5:169-176(1998).
Parry D.A.,et al.Am. J. Hum. Genet. 92:307-312(2013).
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