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UBL4 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P11441
Other Accession NP_055050
Clone Names 3062303
Additional Information
Gene ID 8266
Other Names Ubiquitin-like protein 4A, Ubiquitin-like protein GDX, UBL4A, DXS254E, GDX, UBL4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP2129a was selected from the N-term region of human UBL4 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBL4A
Synonyms DXS254E, GDX, UBL4
Function Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
Cellular Location Cytoplasm, cytosol
Research Areas
Citations (0)

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The UBL4 gene lies in a ubiquitiously transcribed region on the X chromosome approximately 40 kb downstream of glucose-6-phosphate dehydrogenase (G6PD).1 The UBL4 gene, which encodes for a 157 amino acid protein, is consistent with the characteristics of a housekeeping gene, since transcripts are detected a multiple cell types, and the protomoter region is rich in GC sequences and lacks signals such as TATA and CAT boxes. The UBL4 protein bears strong similarity in its 72 N-terminal amino acids to ubiquitin. In the middle of the C-terminus moiety of the UBL4 protein, similarities to the thyroglobulin hormonogenic site, the sequence that surrounds the tyrosines that will form thyroxine, have been demonstrated.2 It has been inferred from these data that the UBL4 protein plays an important role in essential cellular functions.


Chen, E.Y., et al., Hum. Mol. Genet. 5(5):659-668 (1996).Toniolo, D., et al., Proc. Natl. Acad. Sci. U.S.A. 85(3):851-855 (1988).

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$ 80.00
Cat# BP2129a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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