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HERC4 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q5GLZ8
Additional Information
Gene ID 26091
Other Names Probable E3 ubiquitin-protein ligase HERC4, 632-, HECT domain and RCC1-like domain-containing protein 4, HERC4, KIAA1593
Target/Specificity The synthetic peptide sequence is selected from aa 445-459 of HUMAN HERC4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HERC4
Synonyms KIAA1593
Function Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates.
Cellular Location Cytoplasm, cytosol. Note=shows a punctate cytoplasmic distribution
Tissue Location Expressed in brain and testis and detected in heart and placenta.
Research Areas
Citations (0)

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Background

Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates (By similarity).

References

Hochrainer K.,et al.Genomics 85:153-164(2005).
Nagase T.,et al.DNA Res. 7:273-281(2000).
Deloukas P.,et al.Nature 429:375-381(2004).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 80.00
Cat# BP21313c
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