|Other Names||A-kinase anchor protein 8, AKAP-8, A-kinase anchor protein 95 kDa, AKAP 95, AKAP8, AKAP95|
|Target/Specificity||The synthetic peptide sequence is selected from aa 395-410 of HUMAN AKAP8|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II).|
|Cellular Location||Nucleus matrix. Note=Associated with the nuclear matrix. Redistributed and detached from condensed chromatin during mitosis|
|Tissue Location||Highly expressed in heart, liver, skeletal muscle, kidney and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II).
Eide T.,et al.Exp. Cell Res. 238:305-316(1998).
Grimwood J.,et al.Nature 428:529-535(2004).
Olsen J.V.,et al.Cell 127:635-648(2006).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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