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CCR1 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P32246 |
|---|
| Gene ID | 1230 |
|---|---|
| Other Names | C-C chemokine receptor type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, HM145, LD78 receptor, Macrophage inflammatory protein 1-alpha receptor, MIP-1alpha-R, RANTES-R, CD191, CCR1, CMKBR1, CMKR1, SCYAR1 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 343-355 of HUMAN CCR1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CCR1 |
|---|---|
| Synonyms | CMKBR1, CMKR1, SCYAR1 |
| Function | Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP- 1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP- 1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Widely expressed in different hematopoietic cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
References
Neote K.,et al.Cell 72:415-425(1993).
Gao J.-L.,et al.J. Exp. Med. 177:1421-1427(1993).
Nomura H.,et al.Int. Immunol. 5:1239-1249(1993).
Ko J.,et al.FASEB J. 18:890-892(2004).
Sung H.J.,et al.Exp. Mol. Med. 40:332-338(2008).
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