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RABEP1 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q15276
Additional Information
Gene ID 9135
Other Names Rab GTPase-binding effector protein 1, Rabaptin-4, Rabaptin-5, Rabaptin-5alpha, Renal carcinoma antigen NY-REN-17, RABEP1, RAB5EP, RABPT5, RABPT5A
Target/Specificity The synthetic peptide sequence is selected from aa 427-441 of HUMAN RABEP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RABEP1
Synonyms RAB5EP, RABPT5, RABPT5A
Function Rab effector protein acting as linker between gamma- adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.
Cellular Location Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle
Research Areas
Citations (0)

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Background

Rab effector protein acting as linker between gamma- adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.

References

Stenmark H.,et al.Cell 83:423-432(1995).
Nagelkerken B.,et al.Biochem. J. 346:593-601(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Horiuchi H.,et al.Cell 90:1149-1159(1997).

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$ 80.00
$ 99.00
Cat# BP21346c
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