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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PORCN Blocking Peptide (Center)   

PORCN Blocking Peptide (Center)

Synthetic peptide

Product Information
Primary Accession Q9H237
Additional Information
Gene ID 64840
Other Names Protein-cysteine N-palmitoyltransferase porcupine, 231-, Protein MG61, PORCN, MG61, PORC, PPN
Target/Specificity The synthetic peptide sequence is selected from aa 138-151 of HUMAN PORCN
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PORCN (HGNC:17652)
Function Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1), to Wnt proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors.
Cellular Location Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9JJJ7}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9JJJ7}
Tissue Location Isoform 1 is expressed in fetal brain, brain, amygdala, caudate nucleus, cerebellum, hippocampus, pituitary, thalamus, heart, skeletal muscle and testis. Isoform 4 is expressed in amygdala, corpus callosum, hippocampus, spinal cord, kidney, liver, lung, spleen, uterus, testis. Isoform 2 and isoform 3 are expressed in substantia negra, spinal cord, heart and lung
Research Areas
Citations (0)

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protein-cysteine N-palmitoyltransferase that modulates the processing of Wnt proteins by mediating serine palmitoylation of Wnt family members.


Caricasole A.,et al.Gene 288:147-157(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Geraghty M.T.,et al.Submitted (JAN-1993) to the EMBL/GenBank/DDBJ databases.

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$ 80.00
$ 99.00
Cat# BP21406c
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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