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DIP2A Blocking Peptide (Center)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q14689 |
|---|
| Gene ID | 23181 |
|---|---|
| Other Names | Disco-interacting protein 2 homolog A, DIP2 homolog A, DIP2A, C21orf106, DIP2, KIAA0184 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 934-949 of HUMAN DIP2A |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DIP2A |
|---|---|
| Synonyms | C21orf106, DIP2, KIAA0184 |
| Function | Catalyzes the de novo synthesis of acetyl-CoA in vitro (By similarity). Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission (By similarity). Binds to follistatin-related protein FSTL1 and may act as a cell surface receptor for FSTL1, contributing to AKT activation and subsequent FSTL1-induced survival and function of endothelial cells and cardiac myocytes (PubMed:20054002). |
| Cellular Location | Cell membrane; Peripheral membrane protein. Mitochondrion {ECO:0000250|UniProtKB:Q8BWT5}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q8BWT5} |
| Tissue Location | Low expression in all tissues tested. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
May provide positional cues for axon pathfinding and patterning in the central nervous system.
References
Gardiner K.,et al.Genomics 79:833-843(2002).
Tanaka M.,et al.Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hattori M.,et al.Nature 405:311-319(2000).
Nagase T.,et al.DNA Res. 3:17-24(1996).
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