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Mouse Cxxc1 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q9CWW7
Additional Information
Other Names CXXC-type zinc finger protein 1, CpG-binding protein, PHD finger and CXXC domain-containing protein 1, Cxxc1, Cgbp, Pccx1
Target/Specificity The synthetic peptide sequence is selected from aa 364-379 of HUMAN Cxxc1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Cxxc1
Synonyms Cgbp, Pccx1
Function Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.
Cellular Location Nucleus. EMBL; AK010337; BAB26862.1; -; mRNA EMBL; AK083655; BAC38986.1; -; mRNA EMBL; BC030938; AAH30938.1; -; mRNA CCDS; CCDS50320.1; - RefSeq; NP_083144.1; NM_028868.3 UniGene; Mm.17537; - ProteinModelPortal; Q9CWW7; - SMR; Q9CWW7; - BioGrid; 216665; 24 IntAct; Q9CWW7; 21 STRING; 10090.ENSMUSP00000025444; - iPTMnet; Q9CWW7; - PhosphoSitePlus; Q9CWW7; - SwissPalm; Q9CWW7; - EPD; Q9CWW7; - MaxQB; Q9CWW7; - PaxDb; Q9CWW7; - PRIDE; Q9CWW7; - Ensembl; ENSMUST00000025444; ENSMUSP00000025444; ENSMUSG00000024560 GeneID; 74322; - KEGG; mmu:74322; - UCSC; uc008fpg.1; mouse CTD; 30827; - MGI; MGI:1921572; Cxxc1 eggNOG; KOG1632; Eukaryota eggNOG; ENOG410YG6P; LUCA GeneTree; ENSGT00730000111044; - HOGENOM; HOG000116258; - HOVERGEN; HBG051274; - InParanoid; Q9CWW7; - KO; K14960; - OMA; CINITEK; - OrthoDB; EOG091G05JX; - PhylomeDB; Q9CWW7; - TreeFam; TF320326; - ChiTaRS; Cxxc1; mouse PRO; PR:Q9CWW7; - Proteomes; UP000000589; Chromosome 18 Bgee; ENSMUSG00000024560; - CleanEx; MM_CXXC1; - ExpressionAtlas; Q9CWW7; baseline and differential Genevisible; Q9CWW7; MM GO; GO:0005829; C:cytosol; ISO:MGI GO; GO:0035097; C:histone methyltransferase complex; ISO:MGI GO; GO:0016363; C:nuclear matrix; IDA:MGI GO; GO:0016607; C:nuclear speck; ISO:MGI GO; GO:0005634; C:nucleus; ISO:MGI GO; GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB GO; GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IEA:Ensembl GO; GO:0000987; F:proximal promoter sequence-specific DNA binding; ISO:MGI GO; GO:0045322; F:unmethylated CpG binding; ISO:MGI GO; GO:0008270; F:zinc ion binding; IEA:InterPro GO; GO:0051568; P:histone H3-K4 methylation; ISO:MGI GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISO:MGI GO; GO:0006355; P:regulation of transcription, DNA-templated; ISO:MGI GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW InterPro; IPR022056; CpG-bd_C InterPro; IPR037852; CXXC1 InterPro; IPR019786; Zinc_finger_PHD-type_CS InterPro; IPR002857; Znf_CXXC InterPro; IPR011011; Znf_FYVE_PHD InterPro; IPR001965; Znf_PHD InterPro; IPR019787; Znf_PHD-finger PANTHER; PTHR12321:SF58; PTHR12321:SF58; 1 Pfam; PF00628; PHD; 1 Pfam; PF12269; zf-CpG_bind_C; 1 Pfam; PF02008; zf-CXXC; 1 SMART; SM00249; PHD; 1 SUPFAM; SSF57903; SSF57903; 1 PROSITE; PS51058; ZF_CXXC; 1 PROSITE; PS01359; ZF_PHD_1; 1 PROSITE; PS50016; ZF_PHD_2; 1 2: Evidence at transcript level; Acetylation; Activator; Coiled coil; Complete proteome; DNA-binding; Isopeptide bond; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Ubl conjugation; Zinc; Zinc-finger CHAIN 1 660 CXXC-type zinc finger protein 1 /FTId=PRO_0000079744 ZN_FING 28 76 PHD-type. {ECO:0000255|PROSITE- ProRule:PRU00146} ZN_FING 164 213 CXXC-type. {ECO:0000255|PROSITE- ProRule:PRU00509} COILED 426 479 COMPBIAS 156 161 Poly-Gln COMPBIAS 260 321 Asp/Glu-rich (acidic) COMPBIAS 325 363 Arg/Lys-rich (basic) MOD_RES 1 1 N-acetylmethionine {ECO:0000250|UniProtKB:Q9P0U4} MOD_RES 6 6 Phosphoserine {ECO:0000250|UniProtKB:Q9P0U4} MOD_RES 19 19 Phosphoserine {ECO:0000250|UniProtKB:Q9P0U4} MOD_RES 124 124 Phosphoserine {ECO:0000250|UniProtKB:Q9P0U4} MOD_RES 228 228 Phosphoserine {ECO:0000250|UniProtKB:Q9P0U4} MOD_RES 231 231 Phosphothreonine {ECO:0000250|UniProtKB:Q9P0U4} CROSSLNK 254 254 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) {ECO:0000250|UniProtKB:Q9P0U4} SEQUENCE 660 AA; 76167 MW; 9D92CB6DA82069EA CRC64; MEGDGSDLEP PDAGDDSKSE NGENAPIYCI CRKPDINCFM IGCDNCNEWF HGDCIRITEK MAKAIREWYC RECREKDPKL EIRYRHKKCR ERDGSERAGS EPRDEGGGRK RPASDPELQR RAGSGTGVGA MLARGSASPH KSSPQPLVAT PSQHHHQQQQ QQQQQIKRSA RMCGECEACR RTEDCGHCDF CRDMKKFGGP NKIRQKCRLR QCQLRARESY KYFPSSLSPV TPSEALPRPR RPPPTQQQPQ QSQKLGRIRE DEGTVLSSVV KEPPEATATP EPLSDEDLAL DPDLYQDFCA GAFDDHGLPW MSDAEESPFL DPALRKRAVK VKHVKRREKK SEKKKEERYK RHRQKQKHKD KWKHPERADA KDPASLPQCL GPGCVRAAQP GSKYCSDDCG MKLAANRIYE ILPQRIQQWQ QSPCIAEEHG KKLLERIRRE QQSARTRLQE MERRFHELEA IILRAKQQAV REDEENNEND SDDTDLQIFC VSCGHPINPR VALRHMERCY AKYESQTSFG SMYPTRIEGA TRLFCDVYNP QSKTYCKRLQ VLCPEHSRDP KVPADEVCGC PLVRDVFELT GDFCRLPKRQ CNRHYCWEKL RRAEVDLERV RVWYKLDELF EQERNVRTAM TNRAGLLALM LHQTIQHDPL TTDLRSSADR
Research Areas
Citations (0)

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Background

Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.

References

Carninci P.,et al.Science 309:1559-1563(2005).

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$ 80.00
Cat# BP21466c
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