AKR7L Blocking Peptide (N-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8NHP1 |
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Gene ID | 246181 |
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Other Names | Aflatoxin B1 aldehyde reductase member 4, 1---, AFB1 aldehyde reductase 3, AFB1-AR 3, Aldoketoreductase 7-like, AKR7L, AFAR3, AKR7A4 |
Target/Specificity | The synthetic peptide sequence is selected from aa 32-44 of HUMAN AKR7L |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | AKR7L |
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Synonyms | AFAR3 {ECO:0000303|PubMed:12879023}, AKR |
Function | Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity). |
Tissue Location | Mainly expressed in uterus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity).
References
Gregory S.G.,et al.Nature 441:315-321(2006).
Praml C.,et al.Oncogene 22:4765-4773(2003).
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