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CYP7A1 Blocking Peptide (N-term)

Synthetic peptide

     
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Product Information
Primary Accession P22680
Additional Information
Gene ID 1581
Other Names Cholesterol 7-alpha-monooxygenase, CYPVII, Cholesterol 7-alpha-hydroxylase, Cytochrome P450 7A1, CYP7A1, CYP7
Target/Specificity The synthetic peptide sequence is selected from aa 27-38 of HUMAN CYP7A1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP7A1
Synonyms CYP7
Function Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
Cellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
Tissue Location Detected in liver.
Research Areas
Citations (0)

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Background

Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.

References

Nishimoto M.,et al.Biochim. Biophys. Acta 1172:147-150(1993).
Noshiro M.,et al.FEBS Lett. 268:137-140(1990).
Karam W.G.,et al.Biochem. Biophys. Res. Commun. 185:588-595(1992).
Wang D.P.,et al.Genomics 20:320-323(1994).
Molowa D.T.,et al.Biochemistry 31:2539-2544(1992).

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$ 80.00
Cat# BP21523a
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