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Mouse Foxh1 Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession O88621
Additional Information
Gene ID 14106
Other Names Forkhead box protein H1, Forkhead activin signal transducer 1, Fast-1, Forkhead activin signal transducer 2, Fast-2, Foxh1, Fast1, Fast2
Target/Specificity The synthetic peptide sequence is selected from aa 290-302 of HUMAN Foxh1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Foxh1
Synonyms Fast1, Fast2
Function Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).

References

Labbe E.,et al.Mol. Cell 2:109-120(1998).
Liu B.,et al.Mol. Cell. Biol. 19:424-430(1999).
Weisberg E.,et al.Mech. Dev. 79:17-27(1998).
Chen Y.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.

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$ 80.00
Cat# BP21529b
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