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NRGN Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession Q92686
Additional Information
Gene ID 4900
Other Names Neurogranin, Ng, RC3, NEUG(55-78), NRGN
Target/Specificity The synthetic peptide sequence is selected from aa 49-61 of HUMAN NRGN
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRGN
Function Acts as a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity).
Tissue Location In the cerebral cortex, found in the cell bodies of neurons in layers II-VI, and in apical and basal dendrites of pyramidal neurons. Is not found in the dendrites in patients with Alzheimer disease.
Research Areas
Citations (0)

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Background

Acts as a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity).

References

Mertsalov I.B.,et al.Bioorg. Khim. 22:366-369(1996).
Mertsalov I.B.,et al.Bioorg. Khim. 23:961-968(1997).
Martinez de Arrieta C.,et al.Genomics 41:243-249(1997).
Chang J.W.,et al.J. Neuropathol. Exp. Neurol. 56:1105-1118(1997).
Mertsalov I.B.,et al.Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.

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$ 80.00
Cat# BP21561b
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