|Other Names||Serine/threonine-protein phosphatase 6 regulatory subunit 1, SAPS domain family member 1, PPP6R1, KIAA1115, PP6R1, SAPS1|
|Target/Specificity||The synthetic peptide sequence is selected from aa 455-469 of HUMAN PPP6R1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1115, PP6R1, SAPS1|
|Function||Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.|
|Tissue Location||Ubiquitous with higher expression in testis.|
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Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.
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Ohara O.,et al.Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
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Stefansson B.,et al.J. Biol. Chem. 281:22624-22634(2006).
Stefansson B.,et al.Biochemistry 47:1442-1451(2008).
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