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Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O95342 |
|---|
| Gene ID | 8647 |
|---|---|
| Other Names | Bile salt export pump, ATP-binding cassette sub-family B member 11, ABCB11, BSEP |
| Target/Specificity | The synthetic peptide sequence is selected from aa 1083-1097 of HUMAN ABCB11 |
| Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ABCB11 |
|---|---|
| Synonyms | BSEP |
| Function | Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes. |
| Cellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Location | Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ |
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes.
References
Strautnieks S.S.,et al.Nat. Genet. 20:233-238(1998).
Mol O.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Mochizuki K.,et al.Am. J. Physiol. 292:G818-G828(2007).
Jansen P.L.M.,et al.Gastroenterology 117:1370-1379(1999).
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