SRGAP3 Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O43295 |
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Gene ID | 9901 |
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Other Names | SLIT-ROBO Rho GTPase-activating protein 3, srGAP3, Mental disorder-associated GAP, Rho GTPase-activating protein 14, WAVE-associated Rac GTPase-activating protein, WRP, SRGAP3, ARHGAP14, KIAA0411, KIAA1156, MEGAP, SRGAP2 |
Target/Specificity | The synthetic peptide sequence is selected from aa 976-989 of HUMAN SRGAP3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SRGAP3 |
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Synonyms | ARHGAP14, KIAA0411, KIAA1156, MEGAP, SRG |
Function | GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons. |
Tissue Location | Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons.
References
Soderling S.H.,et al.Nat. Cell Biol. 4:970-975(2002).
Endris V.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:11754-11759(2002).
Ishikawa K.,et al.DNA Res. 4:307-313(1997).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Wong K.,et al.Cell 107:209-221(2001).
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