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(DANRE) rab11fip4a Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q3LGD4
Additional Information
Gene ID 436806
Other Names Rab11 family-interacting protein 4A, FIP4-Rab11, Rab11-FIP4-A, zRab11-FIP4-A, rab11fip4a, rab11fip4
Target/Specificity The synthetic peptide sequence is selected from aa 203-216 of HUMAN rab11fip4a
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name rab11fip4a
Synonyms rab11fip4
Function Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity). May play a role in differentiation during retinal development.
Cellular Location Recycling endosome membrane; Peripheral membrane protein. Cleavage furrow. Midbody. Cytoplasmic vesicle. Note=Recruited to the cleavage furrow and the midbody during cytokinesis.
Tissue Location Isoform 1 is predominantly expressed in neural tissues. Isoform B is expressed ubiquitously. In the developing retina, it is expressed in progenitors throughout the retina at early stages and becomes restricted to the ganglion cell layer and ciliary marginal zone as differentiation proceeds
Research Areas
Citations (0)

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Background

Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity). May play a role in differentiation during retinal development.

References

Muto A.,et al.Dev. Biol. 292:90-102(2006).

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$ 80.00
Cat# BP21730c
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