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XPNPEP2 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession O43895
Additional Information
Gene ID 7512
Other Names Xaa-Pro aminopeptidase 2, Aminoacylproline aminopeptidase, Membrane-bound aminopeptidase P, Membrane-bound APP, Membrane-bound AmP, mAmP, X-Pro aminopeptidase 2, XPNPEP2
Target/Specificity The synthetic peptide sequence is selected from aa 393-407 of HUMAN XPNPEP2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name XPNPEP2
Function Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin.
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q95333}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q95333}
Tissue Location Expressed in kidney, lung, heart, placenta, liver, small intestine and colon. No expression in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary
Research Areas
Citations (0)
citation

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Background

A metalloprotease that may play a role in the inflammatory process and other reactions produced in response to injury or infection. May also play a role in the metabolism of the vasodilator bradykinin.

References

Venema R.C.,et al.Biochim. Biophys. Acta 1354:45-48(1997).
Sprinkle T.J.C.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Ryan J.W.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Ross M.T.,et al.Nature 434:325-337(2005).
Duan Q.L.,et al.Am. J. Hum. Genet. 77:617-626(2005).

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$ 277.78
Cat# BP21732c
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Availability: 2 weeks
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