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FAAP24 Blocking Peptide (N-Term)

Synthetic peptide

     
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Product Information
Primary Accession Q9BTP7
Additional Information
Gene ID 91442
Other Names Fanconi anemia-associated protein of 24 kDa, FAAP24, C19orf40
Target/Specificity The synthetic peptide sequence is selected from aa 1-12 of HUMAN FAAP24
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FAP24
Function Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ciccia A.,et al.Mol. Cell 25:331-343(2007).

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$ 80.00
Cat# BP21766a
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