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H1FNT Blocking Peptide (N-Term)

Synthetic peptide

     
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Product Information
Primary Accession Q75WM6
Additional Information
Gene ID 341567
Other Names Testis-specific H1 histone, Haploid germ cell-specific nuclear protein 1, Histone H1t2, H1FNT, HANP1
Target/Specificity The synthetic peptide sequence is selected from aa 79-93 of HUMAN H1FNT
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name H1FNT
Synonyms HANP1
Function Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone- protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1 (By similarity).
Cellular Location Nucleus. Chromosome. Note=In round and elongating spermatids, specifically localizes to a chromatin domain at the apical pole
Tissue Location Testis-specific.
Research Areas
Citations (0)

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Background

Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone- protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1 (By similarity).

References

Huang C.Q.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Scherer S.E.,et al.Nature 440:346-351(2006).
Tanaka H.,et al.Int. J. Androl. 29:353-359(2006).
Martianov I.,et al.Proc. Natl. Acad. Sci. U.S.A. 102:2808-2813(2005).

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$ 80.00
Cat# BP21787a
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