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CRIPAK Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q8N1N5
Additional Information
Gene ID 285464
Other Names Cysteine-rich PAK1 inhibitor, CRIPak, CRIPAK
Target/Specificity The synthetic peptide sequence is selected from aa 154-165 of HUMAN CRIPAK
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRIPAK
Function Negative regulator of PAK1. It has been suggested that the lost of CRIPAK in breast tumors might contribute to hormonal independence.
Cellular Location Cytoplasm. Membrane. Nucleus. Note=Translocated to the nuclear compartment upon hormonal treatment by estrogen
Tissue Location Widely expressed with a highest expression observed in trachea, prostate and adrenal glands. Expressed in many cancer cell lines including breast cancer cells
Research Areas
Citations (0)

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Background

Negative regulator of PAK1. It has been suggested that the lost of CRIPAK in breast tumors might contribute to hormonal independence.

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Talukder A.H.,et al.Oncogene 25:1311-1319(2006).

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$ 80.00
Cat# BP21790c
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