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CSNK2A3 Blocking Peptide (C-Term)

Synthetic peptide

     
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Product Information
Primary Accession Q8NEV1
Additional Information
Gene ID 283106
Other Names Casein kinase II subunit alpha 3, CK II alpha 3, Casein kinase II alpha 1 polypeptide pseudogene, CSNK2A3, CSNK2A1P
Target/Specificity The synthetic peptide sequence is selected from aa 316-330 of HUMAN CSNK2A3
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSNK2A3
Synonyms CSNK2A1P
Function Probable catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Amplification-dependent oncogene; promotes cell proliferation and tumorigenesis by down-regulating expression of the tumor suppressor protein, PML. May play a role in the pathogenesis of the lung cancer development and progression.
Tissue Location Detected in blood platelets and megakaryocyte cell lines. Poorly expressed in lung. Highly expressed in lung tumor tissues.
Research Areas
Citations (0)
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Background

Probable catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Amplification-dependent oncogene; promotes cell proliferation and tumorigenesis by down- regulating expression of the tumor suppressor protein, PML. May play a role in the pathogenesis of the lung cancer development and progression.

References

Wirkner U.,et al.Biochim. Biophys. Acta 1131:220-222(1992).
Devilat I.,et al.FEBS Lett. 316:114-118(1993).
Singh L.S.,et al.Biochemistry 41:8935-8940(2002).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 277.78
Cat# BP21803b
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