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PLA2G4D Blocking Peptide (C-Term)

Synthetic peptide

Product Information
Primary Accession Q86XP0
Additional Information
Gene ID 283748
Other Names Cytosolic phospholipase A2 delta, cPLA2-delta, Phospholipase A2 group IVD, PLA2G4D
Target/Specificity The synthetic peptide sequence is selected from aa 774-786 of HUMAN PLA2G4D
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLA2G4D (HGNC:30038)
Function Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position (PubMed:14709560). May have a substrate specificity for linoleic acid at the sn-2 position (PubMed:14709560).
Cellular Location Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q50L43}. Membrane {ECO:0000250|UniProtKB:Q50L43}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q50L43}; Cytoplasmic side {ECO:0000250|UniProtKB:Q50L43}. Note=Translocates to perinuclear membranes that may correspond to endoplasmic reticulum or Golgi in a calcium-dependent fashion. {ECO:0000250|UniProtKB:Q50L43}
Tissue Location Expressed in stratified squamous epithelia, such as those in skin and cervix, but not in other tissues Strongly expressed in the upper spinous layer of the psoriatic epidermis, expressed weakly and discontinuously in atopic dermatitis and mycosis fungoides, and not detected in the epidermis of normal skin.
Research Areas
Citations (0)

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Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Not arachidonic acid-specific but has linoleic acid-specific activity. May play a role in inflammation in psoriatic lesions.


Chiba H.,et al.J. Biol. Chem. 279:12890-12897(2004).
Zody M.C.,et al.Nature 440:671-675(2006).
Tao R.,et al.Prostaglandins Leukot. Essent. Fatty Acids 73:419-422(2005).

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$ 80.00
Cat# BP21807b
Availability: 2 weeks
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