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TMF1 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession P82094
Additional Information
Gene ID 7110
Other Names TATA element modulatory factor, TMF, Androgen receptor coactivator 160 kDa protein, Androgen receptor-associated protein of 160 kDa, TMF1, ARA160
Target/Specificity The synthetic peptide sequence is selected from aa 467-480 of HUMAN TMF1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMF1
Synonyms ARA160
Function Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP).
Cellular Location Cytoplasm. Nucleus. Golgi apparatus membrane. Note=Concentrated at the budding structures localized at the tips of cisternae
Research Areas
Citations (0)

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Background

Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP).

References

Garcia J.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:9372-9376(1992).
Hsiao P.W.,et al.J. Biol. Chem. 274:22373-22379(1999).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 80.00
Cat# BP21851c
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