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MPP2 Blocking Peptide (C-Term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q14168 |
|---|---|
| Other Accession | Q9WV34 |
| Gene ID | 4355 |
|---|---|
| Other Names | MAGUK p55 subfamily member 2, Discs large homolog 2, Protein MPP2, MPP2, DLG2 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 408-419 of HUMAN MPP2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MPP2 (HGNC:7220) |
|---|---|
| Synonyms | DLG2 |
| Function | Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density (By similarity). In CA1 pyramidal neurons, required for synaptic KCNN2- containing channel function and long-term potentiation expression (By similarity). Seems to negatively regulate SRC function in epithelial cells (PubMed:19665017). |
| Cellular Location | Cytoplasm, cytoskeleton. Membrane Cell projection, dendrite {ECO:0000250|UniProtKB:Q9WV34}. Postsynaptic density {ECO:0000250|UniProtKB:Q9WV34}. Note=Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts. {ECO:0000250|UniProtKB:Q9WV34} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Mazoyer S.,et al.Genomics 28:25-31(1995).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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