|Other Names||SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related, SMARCE1-related protein, BRCA2-associated factor 35, HMG box-containing protein 20B, HMG domain-containing protein 2, HMG domain-containing protein HMGX2, Sox-like transcriptional factor, Structural DNA-binding protein BRAF35, HMG20B, BRAF35, HMGX2, HMGXB2, SMARCE1R|
|Target/Specificity||The synthetic peptide sequence is selected from aa 31-43 of HUMAN HMG20B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||BRAF35, HMGX2, HMGXB2, SMARCE1R|
|Function||Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.|
|Cellular Location||Nucleus. Chromosome. Note=Localized to condensed chromosomes in mitosis in conjunction with BRCA2|
|Tissue Location||Ubiquitously expressed in adult tissues.|
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Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
Sumoy L.,et al.Cytogenet. Cell Genet. 88:62-67(2000).
Marmorstein L.Y.,et al.Cell 104:247-257(2001).
Lee Y.M.,et al.Biochim. Biophys. Acta 1574:269-276(2002).
Wang C.,et al.Biochem. Biophys. Res. Commun. 295:129-135(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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